The Advia 2120i is the updated version of Siemens’ trusted Advia 2120 hematology analyzer. Both systems are built for Complete Blood Count (CBC) testing and WBC differentials, but the 2120i includes new features that make it faster, smarter, and easier to use in busy labs.
If your lab already uses the Advia 2120 or is thinking about upgrading to the Advia 2120i, this article explains what’s new and better. We’ll break down the key differences in design, performance, and lab efficiency.
Overview: Advia 2120 vs. Advia 2120i
1. Improved Software and Interface
One of the biggest upgrades in the Advia 2120i is its software interface. It’s easier to use and faster to navigate. Lab staff can:
Set up tests more quickly
View results with better visuals
Access calibration and QC menus faster
The 2120i also features updated logic for flagging abnormal results, which helps reduce false alarms and improves result reliability.
2. More Stable Reagents and Less Downtime
In the 2120i, Siemens introduced reagent stability improvements. This means:
Longer shelf life
Fewer interruptions
Lower chance of clogs or errors
For labs with high workloads, more stable reagents mean smoother operations and fewer urgent maintenance calls.
3. Better Data Management and LIS Integration
The Advia 2120i has better connectivity to Laboratory Information Systems (LIS). It supports:
Real-time data transfers
Automatic result reporting
Easy export of patient and QC logs
The older 2120 model supports LIS too, but the 2120i offers faster, more reliable connections with updated hospital systems.
4. Enhanced Quality Control Tools
While both models support quality control, the 2120i adds:
Better error alerts
Simplified calibration reminders
More detailed QC reports
This helps labs spot problems sooner and keep test results accurate, especially in settings that require tight regulatory compliance.
5. Slide Maker-Stainer Compatibility
The Advia 2120i works more smoothly with Siemens’ automated slide maker-stainer units. This allows labs to prepare blood smears automatically, saving time and reducing manual steps.
In contrast, the 2120 may require extra setup or may not support full integration with newer slide stainers.
6. Consistent Speed and Sample Handling
Both the Advia 2120 and 2120i offer up to 120 CBCs per hour, and both use closed-tube sampling, barcode scanning, and low sample volumes. So in terms of base testing power, they are similar.
However, the Siemens Advia 2120i maintains this speed more consistently, especially during long runs or mixed testing queues, thanks to better internal automation.
7. Maintenance and Workflow Improvements
The Advia 2120i has smart system alerts that:
Remind staff of routine maintenance
Warn about reagent needs
Help troubleshoot errors faster
These features reduce the training curve for new users and help labs avoid unnecessary downtime.
8. Better Support for High-Volume Labs
The 2120i is more future-ready. It’s built to handle growing lab volumes, modern compliance needs, and digital data workflows.
If your lab is growing, or you’re planning to scale up, the Advia 2120i gives you:
Faster access to patient reports
Better integration with automation systems
Reduced chance of errors from human entry
Use Cases: Which One Is Right for Your Lab?
Choose Advia 2120 if:
You already own the system and it meets your current workload
You have trained staff familiar with its operation
Budget constraints don’t allow for a major upgrade yet
Choose Advia 2120i if:
Your lab is expanding or handling more tests
You need smoother LIS connections and better QC reporting
You want lower downtime and easier maintenance
You’re moving toward full lab automation (including slide prep)
Final Thoughts
The Advia 2120i keeps everything that made the Advia 2120 a reliable hematology analyzer—but makes it better. With stronger software, improved reagent use, better LIS connections, and easier maintenance, the 2120i helps modern labs test smarter and faster.
For labs looking to improve speed, accuracy, and workflow, the Advia 2120i is a smart upgrade built to last.
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